MovDisordV3, Main, Exploration, bibRecord, 000783

Sensorimotor adaptation of speech in Parkinson’s disease

Identifieur interne : 000783 ( Main/Exploration ); précédent : 000782; suivant : 000784

Sensorimotor adaptation of speech in Parkinson’s disease

Auteurs : Fatemeh Mollaei [Canada] ; Douglas M. Shiller [Canada] ; Vincent L. Gracco [Canada, États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2013.

RBID : PMC:3812368

English descriptors

KwdEn :
- Adaptation, Physiological (physiology), Aged, Feedback, Sensory (physiology), Female, Humans, Learning (physiology), Male, Middle Aged, Parkinson Disease (physiopathology), Psychomotor Performance (physiology), Severity of Illness Index, Speech (physiology), Speech Acoustics.
MESH :
- physiology : Adaptation, Physiological, Feedback, Sensory, Learning, Psychomotor Performance, Speech.
- physiopathology : Parkinson Disease.
- Aged, Female, Humans, Male, Middle Aged, Severity of Illness Index, Speech Acoustics.

Abstract

Background

The basal ganglia (BG) are involved in establishing motor plans for a wide range of behaviors. Parkinson’s disease (PD) is a manifestation of basal ganglia dysfunction associated with a deficit in sensorimotor integration and difficulty in acquiring new motor sequences, thereby affecting motor learning. Previous studies of sensorimotor integration and sensorimotor adaptation (SA) in PD have focused on limb movements using visual and force-field alterations.^1–4

Methods

Here we report the results from a SA experiment investigating the ability of PD patients to make speech motor adjustments to a constant and predictable auditory feedback manipulation. Participants produced speech while their auditory feedback was altered and maintained in a manner consistent with a change in tongue position. The degree of adaptation was associated with the severity of motor symptoms.

Results

The PD patients exhibited adaptation to the induced sensory error, however the degree of adaptation was reduced compared to healthy age-matched control participants.

Conclusions

The reduced capacity to adapt to a change in auditory feedback is consistent with reduced gain in the sensorimotor system for speech and with previous studies demonstrating limitations in the adaptation of limb movements following changes in visual feedback in PD patients.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812368

DOI: 10.1002/mds.25588
PubMed: 23861349
PubMed Central: 3812368

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">The basal ganglia (BG) are involved in establishing motor plans for a wide range of behaviors. Parkinson’s disease (PD) is a manifestation of basal ganglia dysfunction associated with a deficit in sensorimotor integration and difficulty in acquiring new motor sequences, thereby affecting motor learning. Previous studies of sensorimotor integration and sensorimotor adaptation (SA) in PD have focused on limb movements using visual and force-field alterations.<sup><xref rid="R1" ref-type="bibr">1</xref>
–<xref rid="R4" ref-type="bibr">4</xref>
</sup>
</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Here we report the results from a SA experiment investigating the ability of PD patients to make speech motor adjustments to a constant and predictable auditory feedback manipulation. Participants produced speech while their auditory feedback was altered and maintained in a manner consistent with a change in tongue position. The degree of adaptation was associated with the severity of motor symptoms.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">The PD patients exhibited adaptation to the induced sensory error, however the degree of adaptation was reduced compared to healthy age-matched control participants.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">The reduced capacity to adapt to a change in auditory feedback is consistent with reduced gain in the sensorimotor system for speech and with previous studies demonstrating limitations in the adaptation of limb movements following changes in visual feedback in PD patients.</p>
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Movement Disorders (revue)

Sensorimotor adaptation of speech in Parkinson’s disease

Sensorimotor adaptation of speech in Parkinson’s disease

Source :

English descriptors

Abstract

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	Movement Disorders (revue)
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